DNA Cytometry for Cervical Cancer Screening in China (DNACIC)

Nanjing Medical University

Status: Completed

Conditions: Cervical Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT00902551

NMU-200703-FC012

NJFY-2007-12901

Details and patient eligibility

About

Very few screenings of any kind will be possible during a woman's lifetime in most low-resource regions, where 80% of the half-million global cases of cervical cancer occur every year. Although a single round of human papillomavirus (HPV) testing was associated with a significant decline in the rate of advanced cervical cancers and associated deaths, whether other methods like as DNA image cytometry can be used as an more accurate means than others in screening cervical cancer or not is yet to be verified. In addition, the accuracy of both DNA image cytometry and conventional cytology is not well known. The investigators hypothesized that DNA image cytometry was superior in screening cervical cancer than conventional cytology.

Enrollment: 25,000 patients

Sex: Female

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Currently or had been married
• Not pregnant
• Had an intact uterus with no prolapse
• Had no history of cervical cancer
• Living in China

Exclusion criteria

• Not willing to participate or finish the study at any time
• History of cervical surgeries

Trial design

25,000 participants in 2 patient groups

1

Description:

Subjects underwent cervical sample DNA image cytometry

2

Description:

Subjects underwent cervical sample conventional cytology