DNA Damage and Subfertility in Males - Impact on ART Outcome (ReproDNA)

Regionshospitalet Viborg, Skive

Status: Enrolling

Conditions: Infertility

Study type: Observational

Funder types: Other

Identifiers

NCT04160208

DFI2019Skivecohort

Details and patient eligibility

About

A obvational prospective cohort study of men undergoing IUI, IVF and ICSI treatment in Denmark. The aim is to asses the impact of sperm DNA damage, measured as DNA fragmentation index (DFI), on reproductive outcomes after assisted reproductive technology (ART).

Enrollment: 1,350 estimated patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• First cycle treatment

Exclusion criteria

• TESA/PESA, more than one cycle

Trial design

1,350 participants in 3 patient groups

IUI - Insemination

Description:

Males of couples undergoing their first IUI treatment

IVF - In vitro fertilisation

Description:

Males of couples undergoing their first IVF treatment. Including males of couples who have had previous IUI treatments.

ICSI - Micro Insemination

Description:

Males of couples undergoing their first ICSI treatment. Including males of couples who have had previous IUI treatments.