DNA Fragmentation - Effect on Pregnancy Rate

Odense University Hospital

Status: Completed

Conditions: Infertility, Male

Treatments: Dietary Supplement: Punalpin; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT05397314

S-20140212

Details and patient eligibility

About

The purpose of this study is to determine whether Punalpin, an antioxidant, has a positive impact on DNA fragmentation in spermatozoa in male fertility patients with increased amount of DNA fragmentation in their spermatozoa. Secondary purpose is to investigate whether there is any positive effect on the subsequent pregnancy rates from the fertility treatment.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male fertility patients with increased amount of DNA fragmentation in their spermatozoa

Exclusion criteria

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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40 participants in 2 patient groups, including a placebo group

Punalpin

Experimental group

Treatment:

Dietary Supplement: Punalpin

Placebo

Placebo Comparator group

Treatment:

Other: Placebo