DNA Mutation Detection in Circulating Tumor DNA and Tissue by mmADPS for Pancreatic Cancer

Seoul National University

Status

Enrolling

Conditions

Pancreatic Cancer

Treatments

Diagnostic Test: cell free DNA in blood, genetic mutation in tissue

Study type

Observational

Funder types

Other

Identifiers

NCT05604573

H-2111-047-1271

Details and patient eligibility

About

Based on the cell free nucleic acid analysis information of blood samples and genetic mutation profile of EUS-FNB tissue from pancreatic cancer, the concordance between them is evaluated. And based on this information, biomarkers for diagnosis, treatment, and prognosis of pancreatic cancer are explored.

Enrollment

150 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients diagnosed with pancreatic cancer through histological or radiologic examination and before treatment begins
Patients aged 18 or older who voluntarily agrees to participate in the study and is willing to understand and comply with the subsequent treatment procedures and sample collection schedule
Among patients diagnosed with benign pancreatic diseases (pancreatic cyst, chronic pancreatitis, etc.), patients who have need for histological examination as control group

Exclusion criteria

Where the subject himself/herself refuses to fill out the consent form or is unable to fill out the consent form
If a laboratory test is impossible due to a qualitative problem with the collected blood sample
Where the collected tissue does not contain tissue of the desired malignant or benign disease