DNI Values After Periodontal Treatment

Kahramanmaraş Sütçü İmam University (KSU)

Status

Completed

Conditions

Periodontitis

Inflammatory Response

Periodontal Inflammation

Treatments

Other: Only routine non-surgical periodontal treatment was applied to the patients.

Study type

Interventional

Funder types

Other

Identifiers

NCT05666622

2020/18-05

Details and patient eligibility

About

The study included 70 systemically healthy individuals, as a test group of 35 patients with Stage 3, Grade A periodontitis and a control group of 35 individuals with no periodontal disease. Blood samples were taken for the examination of DNI, white blood cells (WBC), immature granulocytes (IG), procalcitonin, C-reactive protein (CRP), lymphocyte count and neutrophil count. For the patients with periodontitis, blood sample assays were repeated 3 months after NSPT.

Full description

The role of the Delta Neutrophil Index (DNI) in the pathogenesis and follow-up of periodontal disease has not been comprehensively documented. The study included 70 systemically healthy individuals, as a test group of 35 patients with Stage 3, Grade A periodontitis and a control group of 35 individuals with no periodontal disease. Blood samples were taken for the examination of DNI, white blood cells (WBC), immature granulocytes (IG), procalcitonin, C-reactive protein (CRP), lymphocyte count and neutrophil count. For the patients with periodontitis, blood sample assays were repeated 3 months after NSPT.

Enrollment

70 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients diagnosed with periodontitis
Patients have more than 20 teeth in the mouth
Minimum age 18
Maximum age 65

Exclusion criteria

Patients with any systemic disease
Active smokers
Pregnant or breastfeeding
Patients have used any antibiotic or anti-inflammatory drug in the last 6 months
Patients have received any periodontal treatment in the last 6 months.