Do Low High Density Lipoprotein (HDL) Levels Predict Treatment Outcome in Patients With Chronic Hepatitis C Viral Infection?

Ziv Hospital

Status: Completed

Conditions: Chronic Hepatitis C Viral Infection

Treatments: Other: Responders; Other: Non Responders

Study type: Observational

Funder types: Other

Identifiers

NCT01159613

HDL + HCV

Details and patient eligibility

About

The working hypothesis is that the low HDL serum level predict favorable response to anti viral treatment in chronic HCV (genotype 1) viral infection. This might be used to improve the rate of sustained virologic response.

Full description

Lipoproteins are closely connected to the process of hepatitis C virus (HCV) infection. Metabolic syndrome predicts negative treatment outcome in HCV infection.

Aim: to assess the association between lipids components of the metabolic syndrome and sustained viral response (SVR).

Enrollment: 80 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chronic HCV genotype 1 naive patients

Exclusion criteria

• Co infection with HBV, HIV, HDV
• Decompensated liver disease

Trial design

80 participants in 2 patient groups

Non Responders

Description:

Non Responders

Treatment:

Other: Non Responders

RESPONDERS

Treatment:

Other: Responders