DOC Utility: Screening of Depression, Obstructive Sleep Apnea and Cognitive Impairment

Dr. Richard H. Swartz

Status: Unknown

Conditions: Cognitive Impairment; Stroke; Transient Ischemic Attack; Depression; Obstructive Sleep Apnea

Study type: Observational

Funder types: Other

Identifiers

NCT02363114

1012404 (Other Grant/Funding Number)

141-2014

Details and patient eligibility

About

The primary objective of this study is to determine whether baseline DOC screening can add to clinical and demographic data to predict the occurrence of a composite negative outcome (any of: recurrent stroke, myocardial infarction, death, or admission to a long-term care (LTC) / complex continuing care (CCC) facility) within one year of screening, in stroke prevention clinic patients.

Full description

The DOC screen will be routinely applied to all patients presenting to three high volume Regional Stroke Prevention Clinics (combined first visits >2,800 patients per year). Data will be abstracted from the patient chart using methodologies developed and validated in the Registry of the Ontario Stroke Network. The investigators have REB approval to collect this data and to link with administrative datasets through the Institute for Clinical and Evaluative Sciences (ICES). The investigators will use regression models to determine whether DOC screen scores add to baseline clinical and demographic data to predict the main negative outcomes. The investigators hope to identify which patients presenting to TIA/stroke prevention clinics are at highest risk of adverse long-term events so focused interventions can be developed to improve survival, outcomes and function of stroke prevention clinic patients.

Enrollment: 6,500 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consecutive patients referred to regional stroke prevention clinics.
• This includes those discharged from hospital with a diagnosis of stroke or TIA, as well as emergency department referrals.
• The DOC CRF will also be completed for patients who are unable to complete the screen due to severe aphasia, severe motor dysfunction and language barriers (those who are not fluent in English without translation available).

Exclusion criteria

• Patients whose reason for referral to the clinic is neither Stroke nor TIA, as well as those who have been admitted to LTC/CCC facilities at the time of clinic visit.

Trial design

6,500 participants in 1 patient group

Stroke Prevention Clinic Patients

Description:

All consecutive patients presenting to six high volume Regional Stroke Prevention Clinics.