Does a Multi-ingredient Pre-workout Supplement Enhance Cycling Time Trial Performance? (MIPS)

University of Exeter

Status: Completed

Conditions: Healthy Volunteers

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Ladder Supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT05230862

2021-M-38

Details and patient eligibility

About

The aim of the present study is to test the effect of ingesting a multi-ingredient pre- exercise supplement containing caffeine, creatine, beta-alanine and L-Citrulline compared to a placebo, on endurance exercise performance.

Enrollment: 12 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Exclusion criteria:

• Any diagnosed metabolic health condition
• Pregnant
• Non-habitual caffeine intake
• Smoker
• No endurance training
• Diagnosed Cardiovascular disease
• Recent history of musculoskeletal injury
• Anti-depressant and anti-anxiety medication

Inclusion criteria

• Age 18-40
• Healthy
• Highly trained endurance athletes (V̇O2max: males >55 and females >50 mL⋅kg bm-1⋅min-1)
• Both males and females are allowed to participate. If females are on the oral contraceptive pill they are to be tested on consecutive weeks. If they are not on the oral contraceptive pill, then female subjects are to be tested every 4 weeks, at the same point of their menstrual cycle.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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12 participants in 2 patient groups, including a placebo group

Ladder Supplement

Experimental group

Description:

Ladder Supplement

Treatment:

Dietary Supplement: Ladder Supplement

Placebo

Placebo Comparator group

Description:

Placebo

Treatment:

Dietary Supplement: Placebo