Does Administration of Probiotics During Infancy Increase the Caries Risk of a Child

University of Turku

Status: Withdrawn

Conditions: Dental Caries

Treatments: Dietary Supplement: Probiotics in infant milk formula

Study type: Interventional

Funder types: Other

Identifiers

NCT01424852

Probiotics study7.4.2011

Details and patient eligibility

About

Aim: to examine caries occurrence in children who ten years ago received a mixture of probiotics during infancy.

Hypothesis: the administration of probiotics during infancy has no effect on future dental health.

Sex: All

Ages: 9 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Child participated in the probiotic milk intervention study in early 2000
• Child lives now within 100 km from Turku

Exclusion criteria

• Child has a chronic illness affecting dental health
• Child lives now outside 100 km from Turku

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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0 participants in 2 patient groups, including a placebo group

Probiotics in milk formula

Active Comparator group

Description:

B. lactis BB-12 and L. rhamnosus GG delivered in milk formula during the first year of infancy

Treatment:

Dietary Supplement: Probiotics in infant milk formula

Control milk formula

Placebo Comparator group

Description:

The children received milk formula with no probiotics

Treatment:

Dietary Supplement: Probiotics in infant milk formula