Does Age Matter? Outcomes of Pilon Fracture Fixation in Patients Above and Below 40 Years: A Comparative Study

Cairo University (CU)

Status: Completed

Conditions: Pilon Fracture of Tibia

Treatments: Procedure: staged ORIF of pilon fracture

Study type: Interventional

Funder types: Other

Identifiers

NCT07315581

MS-62-2021

Details and patient eligibility

About

Pilon fractures are severe intra-articular injuries in the distal tibial plafond that result primarily from high-energy axial compression mechanisms such as road traffic accidents or falls from height [1]. They constitute 1-10% of all tibial fractures and frequently involve significant comminution and compromise of the soft-tissue envelope [1,2]. Successful management requires anatomical reduction of the articular surface, restoration of limb alignment, and careful protection of the soft tissues [3].

Since the first description of open reduction and internal fixation (ORIF) for Pilon fractures by Rüedi and Allgöwer in 1969, surgical protocols have evolved from single-stage fixation to a more conservative two-stage approach to reduce wound complications [4-6]. Despite technical advances, treatment outcomes can vary depending on patient-specific factors such as age, comorbidities, and bone quality [7,8].

Younger patients generally exhibit higher bone density and faster healing potential, while patients above 40 years may experience delayed union, increased risk of infection, and reduced functional recovery due to poorer bone perfusion and degenerative changes [9-11]. However, there is limited comparative data examining the impact of age on the success of ORIF in Pilon fractures.

The current study aims to compare clinical and radiographic outcomes of ORIF in patients below and above 40 years, analyzing differences in union rate, complications, and functional recovery using standardized scoring systems.

Enrollment: 56 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Closed, fracture
• Complete articular fracture
• Neither 43-C1, 43-C2, or 43-C3 types based on OTA/AO classification

Exclusion criteria

• Open fractures
• Pathological fractures
• Acute compartment syndrome

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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56 participants in 2 patient groups

Patients < 40 years

Active Comparator group

Description:

Patients in this group had staged ORIF of pilon fracture in younger age

Treatment:

Procedure: staged ORIF of pilon fracture

Patients 40 years or older

Experimental group

Description:

Patients in this group had staged ORIF of pilon fracture

Treatment:

Procedure: staged ORIF of pilon fracture