Does Antibiotic Prophylaxis at Urinary Catheter Removal Prevent Urinary Tract Infections

Omri Schwarztuch Gildor

Status: Invitation-only

Conditions: Urinary Tract Disease; Urologic Diseases

Treatments: Drug: Cefuroxime axetil (trimethoprim/sulfamethoxazole if penicillin allergy)

Study type: Interventional

Funder types: Other

Identifiers

NCT05577273

MMC-0048-18

Details and patient eligibility

About

At the end of most urological procedures, the doctor inserts a urethral catheter for a period of up to 5 days. According to AUA's guidelines, prophylactic antibiotic is indicated during catheter removal.

The aim of our study is to check the influence of the antibiotic treatment on urinary tract infections after catheter removal

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• performing urological operation for other reason

Exclusion criteria

• cannot give informed consent
• <18 years

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

1,000 participants in 2 patient groups

Antibiotic prophylaxis

Experimental group

Description:

Single dose of p.o. antibiotic given 1 hour before catheter removal. The antibiotic of choice is Cefuroxime axetil 500 mg. For penicillin allergy, trimethoprim/sulfamethoxazole 160mg/800mg.

Treatment:

Drug: Cefuroxime axetil (trimethoprim/sulfamethoxazole if penicillin allergy)

No treatment

No Intervention group