Does Benign Prostatic Obstruction Cause Hypertension?

St. Olavs Hospital

Status: Completed

Conditions: Hypertension; Prostatic Hyperplasia

Treatments: Procedure: 24-hr ambulatory blood pressure measurement

Study type: Observational

Funder types: Other

Identifiers

NCT02347436

2014/1117

Details and patient eligibility

About

The known correlation between benign prostatic hypertrophy (BPH) and hypertension could be explained by 3 theoretical pathway models. Whether hypertension causes BPH, BPH causes hypertension or the two are caused by a common factor is currently unknown.

In this study it will be investigated whether hypertension is due to the direct effects of infravesical obstruction to urinary outflow in patients with benign prostatic hyperplasia. The approach will be blood pressure measurement in patients who will have a resection of the prostate.

Enrollment: 20 patients

Sex: Male

Ages: Under 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Listed for inguinal hernia repair or hydrocele repair or transurethral resection of the prostate
• signed informed consent

Exclusion criteria

• Treatment with antihypertensive medication that has been started within 3 months of inclusion.
• Treatment with antihypertensive medication that has been started after inclusion and before final blood pressure measurements have been obtained 6 months after operation.
• Any reason that the investigator deems that the participant will not comply with follow-up.

Trial design

20 participants in 2 patient groups

benign prostatic hypertrophy

Description:

patients who are diagnosed with lower urinary tract symptoms caused by prostatic hypertrophy, undergo transurethral resection of the prostate, and post-surgery 24-hr ambulatory blood pressure measurement.

Treatment:

Procedure: 24-hr ambulatory blood pressure measurement

inguinal hernia or hydrocele

Description:

patients who are diagnosed with lower urinary tract symptoms caused by inguinal hernia or hydrocele, undergo surgical inguinal hernia repair or hydrocele repair, and post-surgery 24-hr ambulatory blood pressure measurement

Treatment:

Procedure: 24-hr ambulatory blood pressure measurement