Does Coenzyme Q 10 Supplementation Reduce Muscle Pain Caused by Statins? (Cholesterol Lowering Medications) (COSMIC)

Hadassah Medical Center

Status: Completed

Conditions: Statin Induced Myalgia

Treatments: Drug: Coenzyme Q 10; Drug: Placebo control

Study type: Interventional

Funder types: Other

Identifiers

NCT00716612

Solgar-080

Details and patient eligibility

About

The purpose of this study is to determine whether Coenzyme Q 10 supplementation will decrease the rate of Muscle Pain in patients with previous statin related Muscle Pain.

Enrollment: 37 patients

Sex: All

Ages: 20 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients treated for hyperlipidemia with a HMG-CoA reductase inhibitor (i.e. pravastatin, simvastatin rosuvastatin or atorvastatin) and reporting myopathic symptoms

Exclusion criteria

• Patients with other identifiable cause of myopathy. Patients with clinical evidence of hepatic, renal, or endocrine disease; coagulopathy; or other serious medical conditions will be excluded.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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37 participants in 2 patient groups, including a placebo group

2

Placebo Comparator group

Description:

PO Placebo QD

Treatment:

Drug: Placebo control

1

Experimental group

Description:

PO Coenzyme Q 10 QD

Treatment:

Drug: Coenzyme Q 10