Does Cold Provocation Increase Brown Adipose Tissue Volume?

University Hospital, Linkoeping

Status: Completed

Conditions: Brown Adipose Tissue, Human

Treatments: Procedure: warm arm; Procedure: cold arm

Study type: Interventional

Funder types: Other

Identifiers

NCT01797328

Dnr2013/41-32 (Other Identifier)

Nystrom_koldstudie

Details and patient eligibility

About

About 28 healthy subjects are randomized to 1 hour/day of coldprovocation or to the best of ability to avoid feeling cold, for 6 weeks. Basal metabolic rate and magnetic resonance (for determination of brown adipose tissue volume) imaging are performed before and after the study.

Enrollment: 28 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: healthy subjects -

Exclusion Criteria: any significant disease, ot other conditions that interferes with magnetic resonance imaging

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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28 participants in 2 patient groups

cold provocation

Active Comparator group

Description:

cold arm

Treatment:

Procedure: cold arm

to avoid feeling cold

Active Comparator group

Description:

warm arm

Treatment:

Procedure: warm arm