Does Coronary Angiography Cause Cognitive Dysfunction?

Karolinska Institute

Status: Completed

Conditions: Heart Valve Diseases; Coronary Heart Disease

Treatments: Procedure: Arterial approach

Study type: Observational

Funder types: Other

Identifiers

NCT01428947

KI-angio-2

Details and patient eligibility

About

The purpose of the study is to study if coronary angiography cause cognitive dysfunction.

Full description

We have previously shown, using transcranial doppler, that coronary angiography cause cerebral microembolism. Cerebral microemboli were more common using the radial than femoral approach. Previously, cerebral microembolism has been associated with new cerebral lesions on MRI. The clinical significance of these new lesions is not determined. The primary aim of this pilot study is to see if coronary angiography cause cognitive dysfunction determined by the MoCA-test. A secondary aim is to relate cognitive dysfunction to cerebral microembolism measured by transcranial doppler. A third aim is to study potential differences between the femoral and radial approaches.

Enrollment: 80 patients

Sex: All

Ages: 35 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective coronary angiography irrespective of cause

Exclusion criteria

• Previous CABG, language problems, not willing to participate

Trial design

80 participants in 1 patient group

Coronary angiography

Description:

Patents scheduled for elective coronary angiography

Treatment:

Procedure: Arterial approach