DOES LOWER BODY PLYOMETRICS CAUSE RHABDOMYOLYSIS IN FEMALE VOLLEYBALL PLAYERS-AN EXPERIMENTAL STUDY

Cairo University (CU)

Status: Completed

Conditions: Rhabdomyolysis; Athletes; Exercise-Induced Muscle Damage

Treatments: Other: plyometric program

Study type: Interventional

Funder types: Other

Identifiers

NCT07352319

BMC VP

Details and patient eligibility

About

Eight-week interventional study to evaluate whether lower-body plyometric training alters serum creatine phosphokinase (CPK) and creatinine levels in female collegiate volleyball players. Sixty participants were randomized to experimental (plyometrics twice weekly) or control (routine volleyball) groups. Blood sampling occurred at baseline; days 2, 4, and 6; and weeks 1, 2, 4, 6, and 8.

Full description

Intervention adapted from James & Robert (2015). Experimental group completed progressive lower-body plyometrics twice weekly (Monday/Wednesday) over eight weeks with warm-up and cool-down. Exercises included squat jump; jump to box (30 cm); tuck jump; split squat jump; lateral hurdle jump (50 cm); zigzag jump; single-leg tuck jump; and depth jump (80 cm). Control group continued routine volleyball activities and did not perform low/medium/high-intensity plyometrics. Primary biomarker (serum CPK) assessed via CK-NAC optimized IFCC method; serum creatinine by modified Jaffe's method. Two-way ANOVA with Bonferroni post hoc used. Findings: CPK increased from day 2, peaked day 4, stabilized to week 2, then declined toward baseline by week 8; creatinine remained stable.

Enrollment: 60 patients

Sex: Female

Ages: 18 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Active collegiate female volleyball players

• consent to participate
• no prior plyometric training program.

Exclusion criteria

• Neuromuscular impairments
• recent injuries.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Lower-body plyometric training

Experimental group

Description:

Progressive plyometric program, twice weekly for eight weeks.

Treatment:

Other: plyometric program

Control

Active Comparator group

Description:

Routine volleyball practice; no plyometric exercises.

Treatment:

Other: plyometric program