Does Meal Replacement With a Carbohydrates and Protein Supplement Induce Weight Loss in Overweight and/or Obese Adults?

Western University, Canada

Status: Unknown

Conditions: Weight Loss

Treatments: Dietary Supplement: Dietary Supplement: Generation UCAN supplementation; Behavioral: satiety

Study type: Interventional

Funder types: Other

Identifiers

NCT04458493

116302

Details and patient eligibility

About

Participants will be randomized into two groups, one group will be the control (no intervention at all) and the other will be CHO-PRO (meal replacement, Generation UCAN supplement, 400ml, 20% solution). Prior to the start of the experiment, all participants will be asked to record their satiety ratings, appetite and desire to eat (10-point visual analogue scale) 30, 60 and 120 minutes after their regular dinner for 3 days. On the first day of the experiment, all participants will be asked to measure their waist and hip circumferences, fasting blood glucose level, maximal number of pushups and body weight using a scale at home prior to breakfast. Instructions on how to do the measurements properly will be recorded in a video and distributed to the participants. Participants in the control group will not receive any intervention. Participants in the CHO-PRO group will be provided with the supplement and they will be asked to consume the CHO - protein supplement (Generation UCAN supplement, 250ml, 10% solution) 6 to 7 hours after lunch, in place of their dinner for 6 weeks. They will also be asked to record their satiety ratings, appetite and desire to eat (10-point visual analogue scale) 30, 60 and 120 minutes after each meal replacement drink. All participants will be required to complete a dietary record, prior to, and during (at weeks 2 and 4) intervention. To track adherence of the CHO-PRO group, participants will be asked to check off the calendar that they did not consume the meal replacement due to various reasons. On day 43, all participants will be asked measure again waist and hip circumferences, fasting blood glucose level, maximal number of pushups and body weight using a scale at home prior to breakfast again.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• sedentary (<2 moderate exercise bouts/wk)
• between the ages of 18 to 40y
• body mass index (BMI) between >25

Exclusion criteria

• do not eat three meals a day typically
• taking medication that affects their eating patterns
• have metabolic and gastrointestinal diseases

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

control

Experimental group

Description:

no supplement will be provided on the day of the experiment

Treatment:

Behavioral: satiety

Generation UCAN

Experimental group

Description:

carbohydrates - protein (Generation UCAN supplement, 400ml, 20% solution)

Treatment:

Behavioral: satiety

Dietary Supplement: Dietary Supplement: Generation UCAN supplementation