Does Meloxicam Provide as Much Pain Relief as Opioids After Shoulder Surgery?

Rothman Institute Orthopaedics

Status and phase: Unknown; Phase 3

Conditions: Shoulder Pain

Treatments: Drug: Meloxicam 15 mg; Procedure: arthroscopic labral repair; Procedure: Preoperative Interscalene Nerve Block

Study type: Interventional

Funder types: Other

Identifiers

NCT04725357

JHOR20D.1216

Details and patient eligibility

About

The opioid epidemic continues to be a major concern, with orthopedic surgeons being among the top prescribers of opioids. Studies evaluating these practices found that opioids are overprescribed, even for common procedures. Patients undergoing arthroscopic labrum repair of the shoulder were found to have an average of 20 pills left over after surgery. Many strategies have been developed to tackle overprescribing and have found success, including no opioid protocols for carpal tunnel release. The purpose of this study is to examine if meloxicam alone provides similar patient reported outcomes to opioids following arthroscopic labrum repair of the shoulder.

Enrollment: 96 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 18
• Scheduled for arthroscopic labrum repair of the shoulder

Exclusion criteria

• History of opioid, acetaminophen, NSAID or local anesthetic allergy or intolerance, or contraindications to these medications.
• Currently on long-term preoperative narcotics
• Scheduled for revision arthroscopic repairs of the shoulder
• Unable/unwilling to consent for enrollment
• Unable to complete postoperative surveys
• History of chronic pain syndromes (fibromyalgia, chronic diffuse MSK pain, etc)
• Patients under the age of 18
• Pregnant or breastfeeding women
• Scheduled for concurrent procedures

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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96 participants in 2 patient groups

Arthroscopic Labral Repair + postoperative Meloxicam

Experimental group

Description:

After surgery participants will receive a prescription of 20 pills of 15 mg Meloxicam

Treatment:

Drug: Meloxicam 15 mg

Procedure: arthroscopic labral repair

Procedure: Preoperative Interscalene Nerve Block

Arthroscopic Labral Repair without Meloxicam

Active Comparator group

Description:

After surgery participants will receive a prescription of 20 pills of 5/300 mg vicodin (hydrocodone/acetaminophen)

Treatment:

Procedure: arthroscopic labral repair

Procedure: Preoperative Interscalene Nerve Block