Does Oral Magnesium Substitution Relieve Pregnancy Induced Leg Cramps ?

University of Oslo (UIO)

Status and phase: Completed; Phase 4

Conditions: Cramps

Treatments: Drug: "Nycoplus Magnesium" (120 mg x 3 daily for 2 weeks)

Study type: Interventional

Funder types: Other

Identifiers

NCT00525317

Oral magnesium in pregnance

Details and patient eligibility

About

This is a trial of treatment with tablets containing magnesium for leg cramps in pregnancy.

Full description

Healthy pregnant women between 18 and 36 weeks of pregnancy suffering from leg cramps at least twice a week were treated with magnesium tablets or placebo for two weeks, 120 mg x 3 daily.

Enrollment: 45 patients

Sex: Female

Ages: 18 to 38 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant women with recurrent leg cramps (at least twice a week).
• No disease according to helath certificate. Written participation consent must be signed.
• Linguistic ability demanded: Norwegian as the first language. Gestation length more than 17 weeks, less than 36 weeks.

Exclusion criteria

• Twin pregnancy.
• Oedema.
• Pre-eclampsia.
• Magnesium supplementation beyond the trial treatment.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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45 participants in 2 patient groups, including a placebo group

Magnesium tablet suplementation (1)

Active Comparator group

Description:

Nycoplus Magnesium" (120 mg x 3 daily for 2 weeks)

Treatment:

Drug: "Nycoplus Magnesium" (120 mg x 3 daily for 2 weeks)

Placebo tablet suplementation (2)

Placebo Comparator group

Description:

Placebo (3 times daily for 2 weeks)

Treatment:

Drug: "Nycoplus Magnesium" (120 mg x 3 daily for 2 weeks)