Does Peri-Operative Gabapentin Reduce Chronic Post-Thoracotomy Pain?
Status and phase
Conditions
Treatments
Study type
Funder types
Identifiers
Details and patient eligibility
About
The primary objective of this study is to determine if gabapentin can decrease or prevent chronic post-thoracotomy pain.
Full description
This study is a prospective double blind randomized controlled trial evaluating the peri-operative use of gabapentin in the prevention or modulation of post-thoracotomy hyperalgesia. Treatment will consist of a 600 mg dose of gabapentin or placebo given preoperatively the night before surgery, based on a computer generated randomized assignment. The treatment group will continue to be medicated with gabapentin 300 mg twice daily for one month following surgery. Those not included in the treatment arm of the study will continue to take a placebo for the same duration. Follow-up will consist of a postoperative visit at approximately 48 hours and a one month clinical visit.
Sex
Ages
Volunteers
Inclusion criteria
- 18 years or older
- Undergoing non-cardiac thoracic surgeries
- Patients determined to have impaired decisional capacity with respect to the provision of informed consent or prisoners will not be included in the study.
Exclusion criteria
- Current gabapentin use or current treatment for neuropathic pain.
- Pregnant or considering becoming pregnant.
Trial design
Primary purpose
Allocation
Interventional model
Masking
0 participants in 2 patient groups, including a placebo group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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