Does Placenta Pathology Predict Outcome of Neonates With Hypoxic Ischemic Encephalopathy?"

University of Zurich (UZH)

Status: Completed

Conditions: Asphyxia Neonatorum

Treatments: Other: hypothermia therapy

Study type: Observational

Funder types: Other

Identifiers

NCT03284528

2017-00912

Details and patient eligibility

About

The histology of the placenta of newborn infants with perinatal asphyxia and hypoxic-ischaemic encephalopathy is analysed. There will be an evaluation if placenta could be a biomarker for neurodevelopmental outcome at 18-24 months of age.

Enrollment: 100 patients

Sex: All

Ages: 1 to 4 days old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:all newborn infants with APGAR <5 at 10minutes, pH<7.0, lactate >12mmol/L, base excess >16, resuscitation >10min after birth, gestational age >35 weeks and an encephalopathy -

Exclusion Criteria: