Does Stellate Ganglion Block Decrease Stress Response of Intubation?

Assiut University

Status and phase: Unknown; Phase 2

Conditions: Intubation; Stellate Ganglion

Treatments: Procedure: stellate block; Drug: lidocaine 2%; Drug: Na.Cl 0.9% (placebo)

Study type: Interventional

Funder types: Other

Identifiers

NCT02732093

irb00008718/654

Details and patient eligibility

About

In this study investigators will evaluate the effect of stellate ganglion block on stress response of intubation in comparison to traditional antistress measures in adult patients

Full description

Both groups will have the same general anesthesia procedure, patients in stellate block group will receive lidocaine in the stellate block will in control group patients will receive Na.Cl as placebo. primary outcome will be stress response to subsequent endotracheal intubation measure by changes in heart rate

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective surgery
• General anesthesia with endotracheal intubation
• ASA I/II

Exclusion criteria

• Pregnancy
• Hypersensitivity to local anesthetics
• Coagulopathy
• Infection at site of injection
• Patient refusal

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups, including a placebo group

stellate block

Active Comparator group

Description:

patients in this arm will receive ultrasonographic guided left stellate block with 6 ml of lidocaine 2% after routine induction of general anesthesia and before endotracheal intubation

Treatment:

Drug: lidocaine 2%

Procedure: stellate block

control

Placebo Comparator group

Description:

patients in this arm will receive ultrasonographic guided left stellate block with 6 ml normal saline (Na.Cl 0.9%) (control group) after routine induction of general anesthesia and before endotracheal intubation

Treatment:

Procedure: stellate block

Drug: Na.Cl 0.9% (placebo)