Does Sunbed Radiation With Mainly UVA Provoke Cutaneous Vitamin D Synthesis in Humans?

Bispebjerg Hospital

Status: Completed

Conditions: Healthy

Treatments: Radiation: UV radiation

Study type: Interventional

Funder types: Other

Identifiers

NCT00516867

KF 01 290815

Details and patient eligibility

About

We would investigate in a controlled, randomized open study in the winter season: 1) If serum levels of vitamin D (25(OH)D) increase in subjects treated with sunbed with sunlamps emitting mainly UVA and only 0·5% or 1·4% UVB compared to non-sunbed treated controls 2) If yes, are the 25(OH)D serum levels then dependent on the UVB dose?

Enrollment: 41 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• Females
• Above 50 years
• Younger with serum concentration of 25(OH)D below 50nmol/l

Exclusion criteria

• No sunbed use last ½ year
• No sun holiday last ½ year
• No intake of vitamin D above 10 microgram/day

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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41 participants in 3 patient groups

UVB 0.5%

Active Comparator group

Treatment:

Radiation: UV radiation

Radiation: UV radiation

Controls

No Intervention group

UVB 1.4%

Active Comparator group

Treatment:

Radiation: UV radiation

Radiation: UV radiation