Does the Use of Ropivacaine Facilitates Cholecystectomy by Laparoscopy in Ambulatory Surgery? (VesiRop)

Centre Hospitalier Departemental Vendee

Status and phase

Completed

Phase 4

Conditions

Laparoscopy

Cholecystectomy

Treatments

Drug: Ropivacaine

Study type

Interventional

Funder types

Other

Identifiers

NCT02085902

CHD 079-13

Details and patient eligibility

About

Since the recommendations of the French Society of Digestive Surgery 2010, cholecystectomy can be performed as outpatient surgery. This approach is difficult in many centers because of post operative pain and nausea/vomiting.

The use of postoperative morphine may be responsible for the state of nausea. The use of ropivacaine allows a reduction of the morphine consumption and thus may allow the patient to have their surgery as an outpatient.

Currently, ropivacaine is used randomly during the investigators surgeries. Initially, it was used for the infiltration holes trocar. In recent years, ropivacaine is used for the reduction of intra-abdominal postoperative pain. Its use is made of parietal surgery ( hernia ) in cholecystectomy and colonic surgery. This mode of administration is allowed to view the many publications made on this subject. Its use in the investigators daily surgery, however, has not been evaluated in ambulatory surgery.

Enrollment

120 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Programmed Cholecystectomy
Laparoscopy
Man and woman
≥ 18
ASA 1 or 2
Not living alone
Patient receiving social security coverage
Signature of Informed Consent Form

Exclusion criteria

Cholecystectomy emergency
Patient minor
Pregnant woman (pregnancy test) or during breastfeeding
Conversion to laparotomy
Patient anticoagulant curative dose
Living alone
Patient addict
Peptic Ulcer
Refusal to enter the protocol
Chronic requiring analgesics long-term
Immunosuppression
Long-term Treatment with corticosteroids
Discovery intraoperative calculation in the bile duct
Contraindication to ropivacaine (see cons-indications to ropivacaine)
Hypersensitivity to study treatment or concomitant medications anesthesia
Cardiac or unbalanced epileptic patients (due to the risk of cardiovascular and neurological local anesthetics)
Patients ASA ≥ 3
Patient <50 kg