Does Topical Lidocaine Decrease Sweat During Exercise in the Heat?

San Diego State University

Status: Completed

Conditions: Sweat Pore Closure

Treatments: Other: control; Drug: Lidocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT05379283

ENS2

Details and patient eligibility

About

Subjects will walk on a treadmill at 3 mph and sweat will be collected from both forearms. One arm will be pretreated with topical lidocaine, and the other will act as the control.

Full description

Subjects will walk on a treadmill at 3 mph and sweat will be collected from both forearms. One arm will be pretreated with topical lidocaine, and the other will act as the control. Sweat will be collected via macroducts attached to each arm. Sweat production on each arm will be compared using t-tests.

Enrollment: 10 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: 18-35 years of age -

Exclusion Criteria: pregnant females

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

lidocaine pretreated skin

Experimental group

Description:

one arm will be pretreated with lidocaine before exercise in the heat

Treatment:

Drug: Lidocaine

Other: control

control skin

No Intervention group

Description:

the other arm will act as the control condition