Does Transfer of Poor-quality Embryos With Good-quality Embryos Improve Pregnancy Outcome in Women Undergoing IVF/ICSI?

Ain Shams University

Status: Completed

Conditions: Infertility

Treatments: Other: Embryo transfer

Study type: Interventional

Funder types: Other

Identifiers

NCT03113097

DAT-055

Details and patient eligibility

About

Women planned to undergo blastocyst-stage embryo transfer after IVF/ICSI were randomized into 2 groups:

• group I: women who had only good-quality embryo transfer.
• group II: women who had both good-quality and poor-quality embryo transfer.

primary outcome was ongoing clinical pregnancy rate

Enrollment: 627 patients

Sex: Female

Ages: 20 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• women undergoing primary IVF/ICSI cycles for tubal factor/unexplained infertility and had blastocyst-stage ET

Exclusion criteria

• cleavage-stage ET.
• women who had no good-quality embryos to transfer
• women who had known poor endometrial receptivity

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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627 participants in 2 patient groups

Good-quality embryo transfer

Active Comparator group

Description:

Women who had only good-quality embryo transfer

Treatment:

Other: Embryo transfer

good- and poor-quality embryo transfer

Active Comparator group

Description:

Women who had both good- and poor-quality embryo transfer

Treatment:

Other: Embryo transfer