Dopaminergic Function and Food Reward

University Hospital Tuebingen

Status: Completed

Conditions: Weight Loss; Adiposity

Treatments: Dietary Supplement: Dopamine depletion vs. Balanced aminoacid drink

Study type: Observational

Funder types: Other

Identifiers

NCT01906411

DAD

Details and patient eligibility

About

The broad aim of the study is to obtain a better understanding of alterations in mesolimbic reward pathways in adiposity based on the hypothesis of a hypofunctioning reward system in obesity.

This will be achieved by integrating a functional neuroimaging (fMRI) with behavioral reward tasks and the modulation of the dopamine level by dopamine depletion.

Enrollment: 36 patients

Sex: Female

Ages: 21 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• female
• healthy

Exclusion criteria

• fMRI contraindications
• claustrophobia

Trial design

36 participants in 1 patient group

subjecst with different BMI

Treatment:

Dietary Supplement: Dopamine depletion vs. Balanced aminoacid drink