Dose-Dependent Effect of Early Antiplatelet Therapy in Acute Ischemic Stroke

Ruhr University of Bochum

Status: Completed

Conditions: Test the Efficacy of Antiplatelet Regimes in Acute Stroke

Study type: Observational

Funder types: Other

Identifiers

NCT01273935

MevesASS01

Details and patient eligibility

About

The aim of this study is to evaluate the low-response prevalence of early antiplatelet therapy and to test the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).

Full description

Antiplatelet agents are important therapeutic options in treating patients with acute ischemic strokes to prevent recurrent ischemic events or death. The aim of this study was to evaluate the low-response prevalence of early antiplatelet therapy and the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).

Enrollment: 400 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• suspected acute cerebrovascular ischemic events and patients who were admitted to the stroke unit where antiplatelet therapy was initiated

Exclusion criteria

• severe liver disorders, current gastrointestinal disorders, congestive heart failure, life-threatening malignancies and a personal or family history of bleeding disorders

Trial design

400 participants in 2 patient groups

Responder

Description:

Responder versus Non-Responder as a result of platelet function test

Non-Responder

Description:

According to the result of platelet function test