Dose-dependent Impact of Daytime Lighting on Evening Responses to Light

Palo Alto Veterans Institute for Research

Status: Not yet enrolling

Conditions: Sleep

Treatments: Behavioral: Light

Study type: Interventional

Funder types: Other

Identifiers

NCT04882280

Reverse DRC

Details and patient eligibility

About

The purpose of this study is to systematically examine the impact of different intensities of daytime light and the subsequent impact that such exposure has on non-image forming responses to light in the evening.

Enrollment: 48 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Aged 18-65
2. Good health
3. Male or female
4. Normal color vision

Exclusion criteria

1. Sleep disorders
2. Extreme chronotypes
3. Routine smoker
4. Significant hearing loss
5. Depressed
6. Alcohol use disorder
7. Use of illegal drugs

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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48 participants in 4 patient groups

Low room

Experimental group

Description:

Low intensity (80 lux) room light

Treatment:

Behavioral: Light

Normal room

Experimental group

Description:

Normal intensity (150 lux) room light

Treatment:

Behavioral: Light

Bright room

Experimental group

Description:

High intensity (500 lux) room light

Treatment:

Behavioral: Light

Bright

Experimental group

Description:

Very high intensity (1000 lux) room light

Treatment:

Behavioral: Light