Dose Low Dose Ketamine in Casesarian

Inonu University

Status: Not yet enrolling

Conditions: Postoperative Pain; Postpartum Depression

Treatments: Drug: Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT06237569

inonu Caesarean

Details and patient eligibility

About

The results of ketamine, ketamine and midazolom and placebo can be copied after birth in cesareans subjected to spinal anesthesia.

Full description

Postpartum depression will be evaluated by dividing the patients into 3 groups: group 1 as ketamine, group 2 as ketamine and midasom, and group 3 as placebo group.

Enrollment: 150 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

American Society of Anesthesiologists 2-.3 18 -45years old Patients planned to be born by cesarean section The patient requests a cesarean section with spinal anesthesia

ExclusionCriteria:

Pathological obstetric complications

Hypertension

Contraindication for ketamine Contraindication for spinal

Trial design

150 participants in 3 patient groups

Grup 1 -Ketamine Group

Description:

Ketamine Group (GROUP 1) 0.5 mg/kg IV single dose bolus diluted to 5 ml with 0.9% saline

Treatment:

Drug: Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia

Group 2-ketamine + midazolam

Description:

Midazolam 0.0125 mg/kg is given followed by a single IV bolus dose of 0.5 mg/kg diluted to 5 ml with 0.9% saline.

Treatment:

Drug: Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia

Group 3-placebo

Description:

Group 3-placebo ;A single dose of IV 5 ml physiological saline will be given.

Treatment:

Drug: Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia