Dose of Labeled Cholesterol for Kinetics: A Pilot Study

Mayo Clinic

Status: Completed

Conditions: Lipid Metabolism

Treatments: Other: stable isotope of cholesterol

Study type: Interventional

Funder types: Other

Identifiers

NCT02065817

13-004890

Details and patient eligibility

About

This is a pilot study to determine the optimum time and dose to draw blood samples using a tracer for HDL kinetics.

Enrollment: 7 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy men and women ages 18 - 50

Exclusion criteria

• Cardiovascular disease
• Metabolic disease
• Hematologic disorder
• Liver or kidney disease
• phenylketonuria
• Currently taking lipid lowering medications or any other drugs that could affect lipid metabolism

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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7 participants in 1 patient group

Tracer

Experimental group

Treatment:

Other: stable isotope of cholesterol