Dose Response of Exercise for Arthritis Management (DREAM)

University of South Carolina

Status: Enrolling

Conditions: Lupus Erythematosus, Systemic; Fibromyalgia (FM); Osteoarthritis; Rheumatoid Arthritis (RA); Arthritis; Gout

Treatments: Behavioral: DREAM Adaptive Intervention

Study type: Interventional

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT06880653

U48DP006850 (U.S. NIH Grant/Contract)

Pro00140006

Details and patient eligibility

About

The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.

Full description

All participants will be randomly assigned a physical activity goal (45 min/week, 90 min/week, or 150 min/week). To help participants achieve goals, they will receive a 6 month program which includes the Arthritis Foundation's Walk With Ease Guidebook, behavioral lessons, a Fitbit, and monthly coaching calls. Participants may also receive additional calls, texts, or emails if they are struggling to meet their physical activity goals.

Enrollment: 285 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years or older
• Have a doctor diagnosed form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia
• Ability to read and write in English

Exclusion criteria

• Have any contraindications to exercise (besides arthritis)
• Engage in ≥30 min/week of Actigraph assessed MVPA
• Are pregnant, breastfeeding, or planning to become pregnant in the next year
• Are planning to relocate out of the Columbia, SC area in the next 12 months,
• Do not have a device compatible with Fitbit
• Have uncontrolled hypertension (e.g., systolic blood pressure > 160 mmHg or diastolic blood pressure > 100 mmHg)
• Plan to have a surgery that affects mobility in the next 12 months
• Have a serious cognitive impairment.
• Not willing to be randomized to any of the 3 conditions, do not believe they could adhere to the goals, or do not believe they could achieve the highest dose of activity (150 minutes/week).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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285 participants in 3 patient groups

45 minutes/week

Experimental group

Description:

Participants will be given a goal of 45 minutes/week of moderate-to-vigorous intensity physical activity

Treatment:

Behavioral: DREAM Adaptive Intervention

90 minutes/week

Experimental group

Description:

Participants will be given a goal of 90 minutes/week of moderate-to-vigorous intensity physical activity

Treatment:

Behavioral: DREAM Adaptive Intervention

150 minutes/week

Experimental group

Description:

Participants will be given a goal of 150 minutes/week of moderate-to-vigorous intensity physical activity

Treatment:

Behavioral: DREAM Adaptive Intervention