Double-blind and Placebo-controlled Study on Intervention Effect of Medium and Long Chain Fatty Acid Triglyceride on Glycolipid Homeostasis in Patients With Metabolic Syndrome and Mechanisms

Zhejiang University

Status: Completed

Conditions: Metabolic Syndrome

Treatments: Dietary Supplement: MLCT supplementation; Dietary Supplement: Olive oil

Study type: Interventional

Funder types: Other

Identifiers

NCT06210230

RCT_MLCT_MetS

Details and patient eligibility

About

Double-blind and placebo-controlled study on intervention effect of medium and long chain fatty acid triglyceride on glycolipid homeostasis in patients with metabolic syndrome and mechanisms

Enrollment: 240 patients

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed metabolic syndrome according to IDF diagnostic criteria;
• Rarely eating out of home;
• Aged between 40 and 70 years.

Exclusion criteria

• Breastfeeding or pregnancy;
• History of heart disease, coronary heart disease, stroke, cerebral infarction, viral liver disease (hepatitis A, hepatitis B, etc.), chronic kidney disease (GFR<60 ml/min) or cancer;
• Diabetic ketoacidosis or hyperketosis;
• Drug use has changed in the past six months;
• Taking insulin;
• Used MLCT edible oil in the past six months;
• Have participated in other clinical trials in the last three months.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

240 participants in 2 patient groups, including a placebo group

Control group

Placebo Comparator group

Treatment:

Dietary Supplement: Olive oil

Intervention group

Experimental group

Treatment:

Dietary Supplement: MLCT supplementation