Double Filtration Plasmapheresis (DFPP) and Lipid Metabolism

Shanghai Pudong Hospital

Status: Unknown

Conditions: DFPP and Platelet Function

Treatments: Device: DFPP

Study type: Interventional

Funder types: Other

Identifiers

NCT03491956

ShanghaiPudongH2

Details and patient eligibility

About

Little clinic trials showed that Double Filtration Plasmapheresis (DFPP) could improve lipid metabolism, however, whether DFPP can improve platelet function and recover Endothelial function is unknown. In this study, we try to confirm the hypothesis that DFPP can improve endothelial function in hyperlipidemia patients.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. hyperlipidemia

Exclusion criteria

1. Severe liver and kidney dysfunction
2. Severe cardiopulmonary insufficiency
3. tumor
4. pregnancy

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

DFPP group

Other group

Description:

self contrast (before and after DFPP)

Treatment:

Device: DFPP