Double Regional Anesthesia in Video Assisted Thoracoscopy (DRAVATS)

University Hospital, Rouen

Status and phase: Completed; Phase 4

Conditions: Video Assisted Thoracoscopy; Anesthesia

Treatments: Drug: paravertebral block; Drug: Serratus plane block and paravertebral block

Study type: Interventional

Funder types: Other

Identifiers

NCT03852862

2017/182/HP

Details and patient eligibility

About

Monocentric, randomized, controlled, single-blind study who's aim is to demonstrate the efficacy of the association of paravertebral block and serratus plane block with paravertebral block alone

Enrollment: 112 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient aged 18 to 75 years;
• Programmed for unilateral videothoracoscopy for anatomical resection (segmentectomy, lobectomy);
• Subject affiliated to a social security scheme;
• Subject having signed an informed consent

Exclusion criteria

• Chronic treatment with opiates;
• Contraindication to administration of morphine;
• Allergy to local anesthetics or contraindications to the use of ropivacaine;
• Contraindication to the realization of paravertebral blocks and serratus;
• Pregnancy, breastfeeding;
• Severe obesity (BMI > 40 kg/m²);
• Renal impairment (GFR < 30 mL/min) or known severe hepatic impairment;
• Difficulties of comprehension preventing the collection of consent and the realization of the study;

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

112 participants in 2 patient groups

Serratus plane block with paravertebral block

Experimental group

Description:

Association of Serratus plane block and paravertebral block for anesthesia

Treatment:

Drug: Serratus plane block and paravertebral block

paravertebral block alone

Active Comparator group

Description:

Paravertebral block for anesthesia

Treatment:

Drug: paravertebral block