Downhill Walking in IPF

Saglik Bilimleri Universitesi

Status: Enrolling

Conditions: Idiopathic Pulmonary Fibrosis (IPF)

Treatments: Other: Treadmill Walking without incline; Other: Pulmonary Rehabilitation; Other: Downhill Walking

Study type: Interventional

Funder types: Other

Identifiers

NCT06756230

Eccentric_IPF

Details and patient eligibility

About

In this study; will examine the effects of downhill walking (eccentric exercise training) on exercise capacity, quality of life, and blood lactate levels in individuals with IPF. After the initial assessment, patients will be randomized into two groups: downhill walking PR group and Standard PR Group.

Full description

Individuals diagnosed with idiopathic pulmonary fibrosis who come to the Pulmonary Rehabilitation Unit of Istanbul Süreyyapaşa Chest Diseases and Chest Surgery Education and Research Hospital will be included in this study. Those who meet the inclusion criteria will be randomized into two groups: Downhill Walking Pr Group (n=17) and Standard Pr Group (n=17). Patients will have exercise sessions twice a week for 8 weeks. Patients will be evaluated immediately before the rehabilitation program and the end of 8 weeks exercise programme. In our study, downhill walking training will differ from traditional walking training only in terms of treadmill training protocol. Traditional walking training involves walking on a motorized treadmill with a neutral incline, progressing with increases in speed, while downhill walking training will be performed at a constant -10% incline.

Enrollment: 34 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Having a diagnosis of IPF according to the clinical diagnostic criteria of the American Thoracic Society and/or the European Respiratory Society (ATS-ERS).
• Being between the ages of 18 and 75.
• Being able to walk on a treadmill.
• Having the ability to cooperate.
• No change in current medication in the last month.
• Not participating in a structured activity program for at least six months.
• Accepting the purpose and method of this study voluntarily and give informed consent for the study.

Exclusion criteria

• Presence of physical or mental impairment that prevents informed consent or compliance with the protocol.
• Inability to attend more than 20% of pulmonary rehabilitation sessions.
• Presence of major cardiovascular disease (coronary artery disease, uncontrolled hypertension, arrhythmias, or heart failure).
• Presence of existing orthopedic and neuromuscular exercise limitations.
• Acute exacerbation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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34 participants in 2 patient groups

Downhill Walking PR Group

Active Comparator group

Description:

A standard pulmonary rehabilitation (PR) exercise program will be implemented. Downhill treadmill walking will be included during walking sessions.

Treatment:

Other: Downhill Walking

Other: Pulmonary Rehabilitation

Standard PR group

Active Comparator group

Description:

A standard pulmonary rehabilitation (PR) exercise program will be implemented. Walking will be performed on a treadmill without incline.

Treatment:

Other: Pulmonary Rehabilitation

Other: Treadmill Walking without incline