Doxapram Administration on Diaphragmatic Excursion in Mechanically Ventilated Patients With Chronic Obstructive Pulmonary Disease Undergoing Spontaneous Breathing Trial

Cairo University (CU)

Status: Enrolling

Conditions: Mechanical Ventilation; COPD; Weaning From Mechanical Ventilation

Treatments: Drug: Doxapram

Study type: Observational

Funder types: Other

Identifiers

NCT07022704

Doxapram in COPD

Details and patient eligibility

About

Researchers aim to evaluate the impact of doxapram administration on diaphragmatic excursion in chronic obstructive pulmonary disease (COPD) patients undergoing spontaneous breathing trial

Full description

doxapram will be administered intravenously (IV) during spontaneous breathing trial. diaphragmatic excursion will be evaluated by an expert in respiratory muscle ultrasound

Enrollment: 35 estimated patients

Sex: All

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with moderate to severe chronic obstructive pulmonary disease undergoing spontaneous breathing trial

Exclusion criteria

• Refusal Allergy to doxapram neuromuscular disorders inability to evaluate the diaphragm

Trial design

35 participants in 1 patient group

Doxapram

Description:

All patients will receive doxapram during spontaneous breathing trial

Treatment:

Drug: Doxapram