Drainage Amount for Removal of Thoracostomy Tube (DARTT)

University of California (UC) Davis

Status: Completed

Conditions: Pneumothorax; Pleural Effusion

Treatments: Other: Drainage <2 mL/kg; Other: No drainage threshold

Study type: Interventional

Funder types: Other

Identifiers

NCT00575198

200715709

Details and patient eligibility

About

The purpose of this study is to determine whether chest tubes can be safely removed without considering how much fluid is draining through the tube.

Full description

Thoracostomy tubes are routinely used to drain the pleural space of fluid and gas to optimize pulmonary mechanics. Clinicians frequently postpone removal of thoracostomy tubes if the drainage from the tube exceeds a specific volume threshold for the prior 24 hours. However, there is substantial variability in the drainage volume threshold that different clinicians use, and no threshold has been established as clearly superior to any other. Removing tubes independently of the drainage volume may result in a greater risk of pleural effusion or pneumothorax requiring an invasive drainage procedure. However, removing tubes independently of the drainage volume might also expedite recovery by allowing earlier removal of the tube, thus diminishing pain and increasing patient mobility.

Thoracostomy tube management practices, including the drainage volume threshold used, may be dissimilar for different types of disease processes, so this study will be restricted to patients who required a thoracostomy tube for treatment of traumatic injury.

Enrollment: 280 patients

Sex: All

Ages: 14+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Thoracostomy tube in place for <72 hours
• Age at least 14 years
• Hospitalized for traumatic injury or elective operation

Exclusion criteria

• Thoracostomy tube already removed from the pleural cavity of interest
• Mediastinal tubes
• Death expected within 48 hours
• Prisoner status
• Severe congestive heart failure
• End-stage liver disease
• End-stage renal disease
• History of or suspected empyema involving the pleural cavity of interest
• History of or anticipated need for pleurodesis of the pleural cavity of interest
• Malignant pleural effusion
• Pregnancy
• Previous participation in this study
• Thoracostomy tube drainage already <2 mL/kg

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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280 participants in 2 patient groups

1

Experimental group

Description:

No drainage threshold

Treatment:

Other: No drainage threshold

2

Active Comparator group

Description:

Drainage \<2 mL/kg

Treatment:

Other: Drainage <2 mL/kg