Drinking Effect of Electrolyzed Alkaline Reduced Water on Oxidative Stress and Fatigue After Intense Exercise

Kyu Jae Lee

Status: Completed

Conditions: Oxidative Stress

Treatments: Device: Electrolyzed alkaline reduced water generator

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT05673395

EMB-2022-02

Details and patient eligibility

About

The goal of this clinical trial is to test the drinking effect of electolyzed alkaline reduced water (ARW) generated from alkaline ionizer (CGM MWPI-2101) on oxidative stress and fatigue after high-intensity exercise in healthy people. The main question[s] it aims to answer are:

• [question 1] Can pH 9.5 EARW reduce oxidative stress compared to purified water (PW)
• [question 2] Can pH 9.5 EARW decrease fatigue markers in blood

Participants will drink water from the experimental device after high-intensity exercise. Blood sample will be collected before exercise, after highly intensive exercise, and after then 15 min. of drinking water.

Researchers will compare EARW group and PW group to see the anti-oxidative and anti-fatigue effects.

Full description

This study was designed as a randomized, controlled, crossover, double-blind clinical trial with a single intervention of ARW intake (pH 9.5, 10 mL/kg body weight) after highly intense exercise.

The participants were divided into two groups, wherein they consumed either purified water (PW group) or EARW (EARW group). Blood samples were collected before exercise, immediately after exercise, and 15 min after drinking water.

For the anti-oxidative effect, ROS, NO, GPx, and MDA levels were measured. For the anti-fatigue effect, latate, lactate dehydrogenase, phosphate and calcium were measured.

Enrollment: 24 patients

Sex: All

Ages: 19 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy male participants aged 19-25 years
• physically active with a normal body mass index (BMI)
• had not smoked for 3 months or consumed alcohol for more than a week prior to the start of the study.

Exclusion criteria

• any kind of visible or known disease
• hypertension,
• musculoskeletal injuries in the previous three months,
• breathing difficulties,
• metabolic diseases,
• autoimmune disease,
• rash,
• urticaria.

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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24 participants in 2 patient groups

EARW group

Experimental group

Description:

This group drink electrolyzed alkaline reduced water (EARW, pH 9.5) 10 mL/kg body weight in 10 min after exercise.

Treatment:

Device: Electrolyzed alkaline reduced water generator

PW group

Sham Comparator group

Description:

PW is purified water generated from sham device, and PW group drink 10 mL/kg body weight in 10 min after exercise.

Treatment:

Device: Electrolyzed alkaline reduced water generator