Drug Interaction Study With NS2359 and Cocaine in Cocaine Experienced Volunteers - 1

National Institutes of Health (NIH)

Status and phase: Unknown; Phase 1

Conditions: Infusions, Intravenous; Drug Administration Schedule; Cocaine-Related Disorders

Treatments: Drug: NS2359

Study type: Interventional

Funder types: NIH

Identifiers

NCT00032916

NIDA-CPU-2359-02-1

Details and patient eligibility

About

The purpose of this study is to conduct a drug interaction study with NS2359 and cocaine in cocaine experienced volunteers.

Full description

This is a single-center, double-blind, placebo-controlled, randomized, single dose, fixed order, dose escalating inpatient design that will study oral NS2359 in cocaine experienced volunteers.

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Male or Female, 18-45 yrs of age; females of child-bearing potential using appropriate method of birth control; be able to understand the procedure and agrees to participate via informed consent; must be cocaine dependent according to DSM-4 criteria; must be capable of providing written consent; must be able to comply with protocol requirement, CPU rules and regulations; must not be currently seeking treatment for cocaine abuse.

Exclusion criteria

Incapable of understanding the informed consent process; Additional criteria available during screening at the site.