DU and BOO in Women With and Without Symptoms of VD

National Taiwan University

Status: Completed

Conditions: Detrusor Underactivity; Bladder Outlet Obstruction

Treatments: Diagnostic Test: Urodynamic study

Study type: Observational

Funder types: Other

Identifiers

NCT04981080

202105082RINA

Details and patient eligibility

About

Women with symptoms of voiding dysfunction may be associated with detrusor underactivity or bladder outlet obstruction. However, the prevalence of detrusor underactivity and bladder outlet obstruction remained obscure. Thus, the aim of this study was to elucidate the prevalence of detrusor underactivity and bladder outlet obstruction in women with and without symptoms of voiding dysfunction.

Full description

Between February 2005 and December 2020, all women with lower urinary tract symptoms but without cystocele who visited the urogynecological department of a medical center for urodynamic evaluation were reviewed. Those women who have no complete data of maximum flow rate, voided volume, post-void residual volume and detrusor pressure at maximum flow rate were excluded from this study. Detrusor underactivity was defined when the detrusor pressure at maximum flow rate was less than 20 cmH2O, the maximum flow rate was less than 15 mL/s, and the bladder voiding efficiency was less than 90 %. Bladder outlet obstruction was defined when the the detrusor pressure at maximum flow rate was not less than 40 cmH2O, and the maximum flow rate was less than 12 mL/s. Those women without detrusor interactivity or bladder outlet obstruction were allocated to the non-DU/BOO group.

STATA software was used for statistical analysis. Chi2 test, univariate and multivariable logistic regression test were used for statistical analysis as appropriate. A p < 0.05 was considered as statistically significant.

Enrollment: 1,886 patients

Sex: Female

Ages: 20 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women with lower urinary tract symptoms
• Complete urodynamic study

Exclusion criteria

• Advanced cystocele
• After surgery for cystocele repair
• Chronic infection
• Incomplete data

Trial design

1,886 participants in 2 patient groups

Symptom of voiding dysfunction

Description:

Women with lower urinary tract symptoms including voiding symptoms but without cystocele who visited the urogynecological department of a medical center for urodynamic evaluation were reviewed

Treatment:

Diagnostic Test: Urodynamic study

No symptom of voiding dysfunction

Description:

Women with lower urinary tract symptoms but without cystocele or voiding symptoms who visited the urogynecological department of a medical center for urodynamic evaluation were reviewed

Treatment:

Diagnostic Test: Urodynamic study