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Dual Arterial Phase Liver CT in Patients With Suspected Portal Hypertension

Seoul National University logo

Seoul National University

Status

Unknown

Conditions

Cirrhosis, Liver
HCC

Treatments

Diagnostic Test: Liver CT

Study type

Interventional

Funder types

Other

Identifiers

NCT04195971
SNUH-2019-2587

Details and patient eligibility

About

Patients with liver cirrhosis is at risk of developing HCC. To diagnose or detect HCC at CT/MRI, optimal late arterial phase (LAP) acquisition is critical to capture the tumor. For LAP acquisition, bolus-tracking is often used at CT. In patients with portal hypertension, however, bolus-tracking occasionally capture early arterial phase which may be related with slow portomesenteric flow. In this study, we obtain dual arterial phase in patients with suspected portal hypertension and determine whether this protocol (dual arterial phase) would provide higher incidence of LAP acquisition than single arterial phase acquisition.

Enrollment

69 patients

Sex

All

Ages

20+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Older than 20 years
  • Liver cirrhosis diagnosed with characteristic imaging feature or histology
  • Presence of portal hypertension sign (splenomegaly and varices)
  • Scheduled for liver CT
  • And signed informed consent

Exclusion criteria

  • Relative or absolute contra-indication of contrast-enhanced CT

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

69 participants in 1 patient group

Liver CT with dual arterial phase
Experimental group
Treatment:
Diagnostic Test: Liver CT

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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