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Dual Energy CT: A New Method for Better Dose Calculation in Proton Beam Therapy ((DUAL))

A

Aarhus University Hospital

Status

Terminated

Conditions

Cancer

Treatments

Other: No intervention

Study type

Observational

Funder types

Other

Identifiers

NCT02722109
VEK52217

Details and patient eligibility

About

Researchers want to compare proton stopping ratios, used for proton beam therapy planning, calculated based on single energy CT and dual energy CT images; with the intension of improve upon the proton range determination.

Full description

The main goal of this study is to compare proton stopping ratios, used for proton beam therapy planning, calculated based on single energy CT and dual energy CT images.

The calculation methods for proton stopping power ratios differs for the two types of CT images, and researchers want to investigate if the proton stopping power ratio can be estimated more accurately by using dual energy CT. A more accurate stopping power ratio calculation gives a more accurate proton range determination in the patient tissue, which again will lead to a better knowledge of the dose distribution in the patient undergoing cancer treatment with proton beam irradiation.

Knowing the accurate dose distribution allows for an uncertainty margin reduction around the tumor, which will result in less normal tissue being irradiated and thereby the risk of side effects is reduced without risking an under-dosage of the tumor.

Enrollment

14 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Cancer patients who are scheduled for a control CT scan

Exclusion criteria

  • Under 18 years of age

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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