Dual Energy CT vs Standard Triple Phase CT-A Randomised Control Trial

All India Institute Of Medical Science (AIIMS)

Status: Completed

Conditions: AML; Renal Cysts; Transitional Cell Carcinoma; Renal Cell Carcinoma

Treatments: Other: Standard multiphase CT; Other: split bolus Dual energy CT

Study type: Interventional

Funder types: Other

Identifiers

NCT02160600

IESC/T-457/29.11.2013

Details and patient eligibility

About

To compare SBDECT with standard Triple Phase Multi-Detector CT (TPMDCT) in renal mass evaluation in terms of appropriateness of treatment received after diagnosis. To determine SBDECT diagnostic accuracy.

Enrollment: 124 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with suspected renal masses needing further evaluation with a contrast enhanced CT scan
• Patients who are referred for CT Urography

Exclusion criteria

• Patients not willing to participate in the study
• Age <18 yrs
• Pregnant females
• Patients with previous h/o serious allergic reactions or Contrast allergy
• Impaired renal function (estimated GFR<45mL/min/mm2)
• Sonographically proven benign renal mass needing no further evaluation

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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124 participants in 2 patient groups

split bolus

Experimental group

Description:

Patients will undergo diagnostic Split bolus DECT scan

Treatment:

Other: split bolus Dual energy CT

Standard

Experimental group

Description:

Patients will undergo routine multiphase diagnostic CT

Treatment:

Other: Standard multiphase CT