Dual Site-Dual Channel Non-invasive Brain Stimulation for Language and Cognitive Function in Healthy Subjects

Samsung Medical Center

Status: Completed

Conditions: Healthy

Treatments: Device: Sham stimulation; Device: DLPFC stimulation; Device: IFG stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT03486808

2017-08-124-D

Details and patient eligibility

About

The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in healthy. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on left inferior frontal cortex, ii) anodal stimulation on left dorsolateral prefrontal cortex. 2) IFG stimulation: anodal stimulation on left inferior frontal cortex; 3) DLPFC stimulation: anodal stimulation on left dorsolateral prefrontal cortex area. 4) sham stimulation

Enrollment: 27 patients

Sex: All

Ages: 19+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy subjects with age over 19 years old

Exclusion criteria

• history of disorders involving central nervous system
• patients with severe medical or psychiatric disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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27 participants in 4 patient groups

Dual stimulation

Experimental group

Description:

i) anodal stimulation of left inferior frontal cortex ii) anodal stimulation on left dorsolateral prefrontal cortex

Treatment:

Device: DLPFC stimulation

Device: IFG stimulation

IFG stimulation

Active Comparator group

Description:

anodal stimulation of left inferior frontal cortex

Treatment:

Device: IFG stimulation

DLPFC stimulation

Active Comparator group

Description:

anodal stimulation on left dorsolateral prefrontal cortex

Treatment:

Device: DLPFC stimulation

Sham stimulation

Sham Comparator group

Description:

sham stimulation

Treatment:

Device: Sham stimulation