Dual Site-Dual Channel Non-invasive Brain Stimulation for Motor Function in Healthy Subjects

Samsung Medical Center

Status: Completed

Conditions: Healthy

Treatments: Device: M1 stimulation; Device: PMC stimulation; Device: Sham stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT03486795

2017-08-124-C

Details and patient eligibility

About

The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in healthy subjects. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex, ii) anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area. 2) M1 stimulation: anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex; 3) PMC stimulation: anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area. 4) sham stimulation

Enrollment: 27 patients

Sex: All

Ages: 19+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy subjects with age over 19 years old

Exclusion criteria

• history of disorders involving central nervous system
• patients with severe medial or psychiatric disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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27 participants in 4 patient groups

Dual stimulation

Experimental group

Description:

1. anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex 2. anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area

Treatment:

Device: M1 stimulation

M1 stimulation

Experimental group

Description:

anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex

Treatment:

Device: M1 stimulation

PMC stimulation

Experimental group

Description:

anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area

Treatment:

Device: PMC stimulation

Sham stimulation

Sham Comparator group

Description:

Sham stimulation

Treatment:

Device: Sham stimulation