Dual Task Aerobic Exercise for Older Adults With Cognitive Impairment (HM2)

Parkwood Hospital, London, Ontario

Status: Completed

Conditions: Cognitive Impairment

Treatments: Behavioral: Exercise Intervention; Behavioral: Exercise Control

Study type: Interventional

Funder types: Other

Identifiers

NCT01572311

DAE-1234

Details and patient eligibility

About

The investigators proposed research will establish whether combining aerobic exercise with cognitive challenges is feasible and effective in community dwelling older adults with early signs of cognitive impairment.

Full description

To determine the effects of dual-task aerobic exercise training on community dwelling older adults with early signs of cognitive impairment. We will compare an exercise intervention (E-I) versus an exercise control (E-C) group. Each week, both groups will accumulate a minimum of 120 minutes of exercise (target 150 minutes) from community-based group classes (50 minutes of aerobic exercise) and also complete 45 minutes of beginner-level Square Stepping Exercise (SSE). The E-I group will also answer cognitively challenging questions while doing SSE (dual-task training). This study will determine whether a combined multiple modality (primary component being aerobic exercise) and dual-task exercise program is both feasible and effective for improving cognitive and mobility status, as well as vascular compliance, in older adults who may be at risk for cognitive and mobility decline.

Enrollment: 44 patients

Sex: All

Ages: 55 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male/Female 55-90 years old.
• Montreal Cognitive Assessment score ≤27
• Preserved Instrumental Activities of Daily Living (based on Lawton-Brody Instrumental Activities of Daily Living Sale)

Exclusion criteria

• Dementia (i.e., Mini-Mental Examination score <24 or self-reported physician diagnosis)
• Major Depression (>=16 on the Center for Epidemiologic Studies - Depression Scale combined with clinical judgment by primary study physician)
• Other neurological or psychiatric disorders
• Recent history of severe cardiovascular conditions
• Significant orthopedic conditions
• Have blood pressure >180/100 mmHg or <100/60 mmHg
• Unable to comprehend questionnaire material/study procedures

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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44 participants in 2 patient groups

Exercise Intervention Group

Experimental group

Description:

For 26 weeks, attend Canadian Centre for Activity and Aging combined classes (75-minute or 60-minute classes, 2 to 3 days/week) and also complete 45 minutes of dual-task gait training (15 minutes for 3 days/week or 22.5 minutes for 2 days/week)

Treatment:

Behavioral: Exercise Intervention

Exercise Control group

Active Comparator group

Description:

For 26 weeks, attend Canadian Centre for Activity and Aging combined classes (75-minute or 60-minute classes, 2 to 3 days/week) and also complete 45 minutes of gait training (15 minutes for 3 days/week or 22.5 minutes for 2 days/week). Note: no dual-task challenges during gait training

Treatment:

Behavioral: Exercise Control