Dual-task Assessment and Rehabilitation for Individuals With Residual Symptoms After mTBI

Allina Health System

Status: Completed

Conditions: Brain Injury Traumatic Mild; Concussion, Brain

Treatments: Behavioral: Cognitive and Motor Dual-task Intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT03478059

CKMW-1701

Details and patient eligibility

About

This research aims to develop an intervention that combines mTBI-specific motor and cognitive challenges into a progressive and challenging rehabilitation program. We plan to develop and refine a combined motor and cognitive intervention using healthy athletic young adults (n=12) and people with a positive history of non-resolving mTBI (n=12). We will conduct limited feasibility testing by conducting 6 week training sessions with each subject group. We also plan to identify best measures for determining readiness for duty or full function by incorporating and testing 3 dual-task assessment measures using state-of-the-art wearable sensors to quantify movement.

Enrollment: 24 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria-healthy control:

• Adults aged 18-34 years of age.
• Strong history of athletic participation including high school and collegiate varsity and/or club sports
• Current sport or recreational sport participation at least 3 days per week
• Willingness to participate in 3 times a week 60 minute exercise program conducted at Courage Kenny Research Center (CKRC).

Exclusion Criteria-healthy control:

• History of concussion.
• History of orthopedic or neurologic diagnosis (stroke, multiple sclerosis, Parkinson's Disease, etc.) interfering with subject's ability to exercise
• Unwilling to exercise.
• At risk for cardiopulmonary disease as defined by the American College of Sports Medicine.
• Active medical contraindications by self-report after explanation of dual-task exercise program.
• Active chemical dependency or major psychiatric disorders (ie., schizophrenia, major psychosis) by self-report.

Inclusion criteria-subjects with mTBI residual symptoms:

• Adults aged 18-50 years of age.
• Self-report of some consistent exercise or activity a minimum of 2-3 days per week.
• 3 weeks to 24 months post most recent concussion seeking treatment at Courage Kenny Rehabilitation Institute (CKRI) clinics
• Willingness to participate in 3 times a week 60 minute exercise program conducted at CKRC.

Exclusion Criteria- subjects with mTBI residual symptoms:

• History of orthopedic or neurologic diagnosis (stroke, multiple sclerosis, Parkinson Disease, etc.) interfering with subject's ability to exercise
• Unwilling to exercise.
• At risk for cardiopulmonary disease as defined by the American College of Sports Medicine.
• Active medical contraindications by self-report after explanation of dual-task exercise program,
• Active chemical dependency or major psychiatric disorders (ie., schizophrenia, major psychosis).

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 2 patient groups

Mild Traumatic Brain Injury

Experimental group

Description:

60 minute, 3 times per week, 6 week long Cognitive and Motor Dual-task Intervention program. The intervention will consist of 6 stations that target known motor and cognitive impairments after mTBI. Subjects with mTBI residuals will be gently progressed through exercise stations in an individually tailored fashion.

Treatment:

Behavioral: Cognitive and Motor Dual-task Intervention

Healthy Control

Other group

Description:

60 minute, 3 times per week, 6 week long Cognitive and Motor Dual-task Intervention program. The intervention will consist of 6 stations that target known motor and cognitive impairments after mTBI. In addition to providing comparison data, the healthy control, athletic 18-34 year old subjects will be used to identify levels and intensity of progressions of dual-task training stations appropriate for highly trained athletes and military personnel recovering from concussion.

Treatment:

Behavioral: Cognitive and Motor Dual-task Intervention