Dual Task in Duchenne Muscular Dystrophy

Hacettepe University

Status: Completed

Conditions: Duchenne Muscular Dystrophy

Treatments: Other: 10 meter walk test

Study type: Interventional

Funder types: Other

Identifiers

NCT05575648

2022/13-45

Details and patient eligibility

About

This study was planned to determine the effects of the dual-task performance of children with DMD with motor dysfunction and varying degrees of cognitive impairment compared to their healthy peers, to compare the dual-task performance of children with different functional levels, and to determine the relationship between parameters that may affect dual-task performance.

Full description

Children who are at least 6 years old and who can walk 10 meters independently, whose Duchenne's muscular dystrophy (DMD) diagnosis has been confirmed as a result of genetic testing, will be included in the study. To determine dual-task performance, the 10-meter Walk Test will be performed with additional motor and cognitive tasks. Functional level (Brooke Lower Extremity Functional Classification), ambulation level (North Star Ambulation Rating), muscular performance and functions (6 Minute Walk Test), balance (Pediatric Berg Balance Scale and four square step test), fear of falling (Fear of Falling Questionnaire), gait (Gait in DMD Assessment Scale, Gait Quality and Independence Classification Scale in DMD, and Functional Evaluation Scale for Duchenne Muscular Dystrophy-Gait Domain (FES-DMD-GD)), cognitive level (Modified Mini-Mental State Test (MMDT)), independence and activity limitation (Pediatric Functional Independence Measure (WeeFIM) and ACTIVLIM), quality of life (The Pediatric Quality of Life Inventory (PedsQL)-Neuromuscular Module Turkish version PedsQL-3.0 Neuromuscular Module) will be evaluated.

Enrollment: 94 patients

Sex: Male

Ages: 6+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Having been diagnosed with DMD by a pediatric neurologist,
• Must be at least 6 years old and have the ability to walk 10 meters independently,
• Being able to cooperate with the instructions given by the physiotherapist,
• Not having undergone surgery in the last 6 months and not having any injuries,

Exclusion criteria

• Failure to cooperate with the physiotherapist who made the evaluations,
• Have had any injury and/or surgery in the last 6 months,
• Children without consent will not be included.

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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94 participants in 2 patient groups

Duchenne Muscular Dystrophy

Other group

Description:

Children who have been diagnosed with Duchenne Muscular Dystrophy.

Treatment:

Other: 10 meter walk test

Healthy Subjects

Active Comparator group

Description:

Children who have a normal motor and cognitive development.

Treatment:

Other: 10 meter walk test