Dual-task Performance in Young-onset PD

National Yang Ming Chiao Tung University

Status: Unknown

Conditions: Early Stage Parkinson Disease; Early Onset Parkinson Disease

Treatments: Other: Treadmill training; Other: Game based dual-task training

Study type: Interventional

Funder types: Other

Identifiers

NCT04033393

2019-05-005C

Details and patient eligibility

About

This study aimed to investigate the effects of Game based dual-task training with treadmill on executive function and dual-task performance in individuals with early-onset PD and discuss the correlation between the change values of executive function and dual-task performance after training. Besides, investigate cortical activation after training.

Enrollment: 40 estimated patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed as PD and Hoehn and Yahr stage between 1~3
• Age between 20 to 80
• Able to walk 10 m independently without an assistive device
• A score of greater than or equal to 24 on the mini-mental state examination (MMSE)
• In stable medical condition allowing participation in the testing protocol and intervention

Exclusion criteria

• Any comorbidity or disability other than PD that would preclude gait training
• Any uncontrolled health condition for which exercise was contraindicated
• Any neurological or orthopedic disease that might interfere with the study
• Server freezing of gait, FOG questionnaire > 15

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Game based dual-task training group

Experimental group

Description:

Participants in dual-task training group will execute game based dual-task training with treadmill, 3 times per week for 8 weeks

Treatment:

Other: Game based dual-task training

Treadmill training group

Active Comparator group

Description:

Participants in treadmill training group will do treadmill training, 3 times per week for 8 weeks

Treatment:

Other: Treadmill training